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Perinatal Outcome in Women with Hypertensive Disorders of Pregnancy in Rural Tertiary Center of Northern India: A Retrospective Cohort Study

Author(s):

Naina Kumar* and Ashu Yadav  

Abstract:


Background: Hypertensive disorder of pregnancy is associated with adverse maternal, perinatal outcome.

Objective: To know perinatal outcome in women with hypertensive disorders of pregnancy.

Methods: Present retrospective cohort study was conducted in Obstetrics and Gynecology department of rural tertiary center of Northern India over one year (January-December 2018) on 205 antenatal women with hypertensive disorders of pregnancy at gestation ≥28 weeks. All the participants on the basis of diagnosis were divided into four groups: Group 1 Gestational hypertension; Group 2 Pre-eclampsia; Group 3 Eclampsia and Group 4 with Chronic Hypertension. Demographic features, gestational age, onset of labor, mode of delivery, and perinatal outcome including birthweight, Apgar scores, morbidity and mortality were recorded and compared between four groups. Statistical analysis was done using software SPSS 22.0. version.

Results: Of 205 participants, 93 had Gestational Hypertension, 68 Pre-eclampsia; 36 Eclampsia, 06 Chronic Hypertension. Mean age of presentation was 24.96±3.535 years. Average gestation for group 1 was 37.91±2.38 weeks, group 2: 36.50±3.312 weeks, group 3: 34.44±4.062 weeks and group 4: 37.97±1.524 weeks. Majority of participants had induced labor especially in pre-eclampsia and eclampsia group (p=0.000) with spontaneous vaginal delivery as most common mode. 1 and 5-minute Apgar scores, birthweight were significantly lower in eclampsia and pre-eclampsia women (p<0.05). A significant correlation was observed between severity of disease and perinatal outcome with more morbidity and mortality in eclampsia and pre-eclampsia group (p<0.05).

Conclusion: Hence, hypertensive disorder of pregnancy was associated with adverse perinatal and maternal outcome which was directly related to disease severity.

Keywords:

Birth weight, Gestation, Pregnancy, Neonate, Perinatal, Hypertension

Affiliation:

Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Mangalagiri-522503 Guntur, Andhra Pradesh, Department of Obstetrics and Gynecology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana-133207 Ambala, Haryana



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