Paolo Quitadamo*, Sara Isoldi, Saverio Mallardo, Letizia Zenzeri and Giovanni Di Nardo
Irritable bowel syndrome (IBS) is the commonest cause of recurrent abdominal pain in children in both more developed and developing parts of the world. It is characterized by abdominal pain that is improved by defecation and whose onset is associated with a change in stool form and/or frequency and is not explained by structural or biochemical abnormalities. A number of potential patho-physiological mechanisms have been described, but so far the exact underlying etiology of IBS is unclear. Likewise, no optimal treatment has ever been found neither for adult nor for pediatric patients. Current therapeutic options include drugs, dietary interventions and biopsychosocial therapies. The present review aims at evaluating the scientific evidence supporting the efficacy of these treatments for children with IBS.
irritable bowel syndrome, functional gastrointestinal disorders, children
Department of Pediatrics, A.O.R.N. Santobono-Pausilipon, Naples, Maternal and Child Health Department, Sapienza - University of Rome, Santa Maria Goretti Hospital, Polo Pontino, Latina, Maternal and Child Health Department, Sapienza - University of Rome, Santa Maria Goretti Hospital, Polo Pontino, Latina, Pediatric Emergency Unit, Santobono-Pausilipon Children's Hospital, Naples, Chair of Pediatrics, Pediatric Gastroenterology and Endoscopy Unit, NESMOS Department, FacultySchool of Medicine and Psychology, Sapienza University of Rome, Sant’Andrea University Hospital, Rome