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Neonatal Persistent Pulmonary Hypertension Associated with Congenital Cystic Adenomatoid Malformation Treated with Sildenafil: Case Report

[ Vol. 5 , Issue. 2 ]

Author(s):

Gianfranco Maffei, Vincenzo Manuppelli and Rosario Magaldi   Pages 85 - 88 ( 4 )

Abstract:


We report a case with severe persistent pulmonary hypertension (PPHN) associated with congenital cystic adenomatoid malformation of the lung (CCAM) treated with sildenafil PO. The case was unresponsive to the High-Frequency Oscillatory Ventilation (HFOV), with a oxygenation index (OI) of 50 before sildenafil. Substantial improvement in OI was followed by extubation and survival. No side-effects were noted.

Keywords:

PPHN, CCAM, sildenafil, HFOV, oxygenation index

Affiliation:

Neonatal Intensive Care Unit, “Ospedali Riuniti”, Foggia Hospital, S N L Pinto STR., Foggia, 71100, Italy.



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