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The Role of Probiotics in the Prevention of Necrotizing Enterocolitis

[ Vol. 15 , Issue. 2 ]


Ivana Trivić, Ana Savić Mlakar and Iva Hojsak*   Pages 88 - 91 ( 4 )


Necrotizing enterocolitis (NEC) is a frequent and severe life-threatening disease affecting the gastrointestinal tract of preterm infants. Given that NEC occurs in a well-defined population of patients, there might be a considerable benefit in identifying specific pharmacological and nutritional preventive strategies, that could reduce the incidence of NEC. Amongst nutritional strategies emphasis has been put on the use of probiotics. Therefore, the aim of this review is to summarize currently available evidence on the role of probiotics in general, as well as the role of specific probiotic strains or their combinations, in the prevention of NEC.


Premature infant, microbiota, sepsis, neonate, NEC, patients, probiotics.


Children's Hospital Zagreb, Zagreb, Center for Research and Knowledge Transfer in Biotechnology, University of Zagreb, Zagreb, Children's Hospital Zagreb, Zagreb

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